
Welcome to Gladyshev Lab Website
Areas of interest:
Thiol-based redox regulation and signaling
Identity and functions of selenocysteine-containing proteins
Mechanism of cancer prevention by selenium
Bioinformatics
Redox biology
Aging
Latest publications from the lab
General trends in trace element utilization revealed by comparative genomic analyses of Co, Cu, Mo, Ni and Se. Zhang Y., Gladyshev V.N. J Biol Chem., Nov 2. [Epub ahead of print]
Selenoproteins regulate macrophage invasiveness and extracellular matrix-related gene expression. Carlson B.A., Yoo M.H., Sano Y., Sengupta A., Kim J.Y., Irons R., Gladyshev V.N., Hatfield D.L., Park J.M. BMC Immunol., 10: 57.
Structural analysis of cysteine S-nitrosylation: A modified acid-based motif and the emerging role of trans-nitrosylation. Marino S.M., Gladyshev V.N. J Mol Biol., Oct 22. [Epub ahead of print]
Endothelial nitric oxide synthase negatively regulates hydrogen peroxide-stimulated AMP-activated protein kinase in endothelial cells. Jin B.Y., Sartoretto J.L., Gladyshev V.N., Michel T. Proc Natl Acad Sci USA, 106: 17343-17348.
Recode-2: new design, new search tools, and many more genes. Bekaert M., Firth A.E., Zhang Y., Gladyshev V.N., Atkins J.F., Baranov P.V. Nucleic Acids Res., Sep 25. [Epub ahead of print]
Delineating the role of glutathione peroxidase 4 in protecting cells against lipid hydroperoxide damage and in Alzheimer's disease. Yoo M.H., Gu X., Xu X.M., Kim J.Y., Carlson B.A., Patterson A.D., Cai H., Gladyshev V.N., Hatfield D.L. Antioxid Redox Signal., Sep 21. [Epub ahead of print]

