
Welcome to Gladyshev Lab Website
Areas of interest:
Thiol-based redox regulation and signaling
Identity and functions of selenocysteine-containing proteins
Mechanism of cancer prevention by selenium
Bioinformatics
Redox biology
Aging
Latest publications from the lab
dbTEU: a protein database of trace element utilization. Zhang Y., Gladyshev V.N. (2010) Bioinformatics, Jan 6. [Epub ahead of print]
CUG start codon generates thioredoxin/glutathione reductase isoforms in mouse testes. Gerashchenko M.V., Su D., Gladyshev V.N. (2009) J Biol Chem., Dec 14. [Epub ahead of print]
Selenoprotein T deficiency alters cell adhesion and elevates selenoprotein W expression in murine fibroblast cells. Sengupta A., Carlson B.A., Labunskyy V.M., Gladyshev V.N., Hatfield D.L. (2009) Biochem Cell Biol., 87: 953-961.
General trends in trace element utilization revealed by comparative genomic analyses of Co, Cu, Mo, Ni and Se. Zhang Y., Gladyshev V.N. (2009) J Biol Chem., 285: 3393-3405.
Selenoproteins regulate macrophage invasiveness and extracellular matrix-related gene expression. Carlson B.A., Yoo M.H., Sano Y., Sengupta A., Kim J.Y., Irons R., Gladyshev V.N., Hatfield D.L., Park J.M. (2009) BMC Immunol., 10: 57.
Structural analysis of cysteine S-nitrosylation: A modified acid-based motif and the emerging role of trans-nitrosylation. Marino S.M., Gladyshev V.N. (2009) J Mol Biol., 395: 844-859.

