2022 Articles
Epigenetic aging of the demographically non-aging naked mole-rat
Kerepesi C, Meer MV, Ablaeva J, Amoroso VG, Lee SG, Zhang B, Gerashchenko MV, Trapp A, Yim SH, Lu AT, Levine ME, Seluanov A, Horvath S, Park TJ, Gorbunova V, Gladyshev VN.
Nature communications
doi: 10.1038/s41467-022-27959-9
Rapamycin treatment during development extends life span and health span of male mice and Daphnia magna
Shindyapina AV, Cho Y, Kaya A, Tyshkovskiy A, Castro JP, Deik A, Gordevicius J, Poganik JR, Clish CB, Horvath S, Peshkin L, Gladyshev VN.
Science advances
doi: 10.1126/sciadv.abo5482
Emerging rejuvenation strategies-Reducing the biological age
Zhang B, Trapp A, Kerepesi C, Gladyshev VN.
Aging cell
doi: 10.1111/acel.13538
Selenocysteine Machinery Primarily Supports TXNRD1 and GPX4 Functions and Together They Are Functionally Linked with SCD and PRDX6
Santesmasses D, Gladyshev VN.
Biomolecules
doi: 10.3390/biom12081049
The selenoprotein methionine sulfoxide reductase B1 (MSRB1)
Tarrago L, Kaya A, Kim HY, Manta B, Lee BC, Gladyshev VN.
Free radical biology & medicine
doi: 10.1016/j.freeradbiomed.2022.08.043
Selenoprotein TXNRD3 supports male fertility via the redox regulation of spermatogenesis
Dou Q, Turanov AA, Mariotti M, Hwang JY, Wang H, Lee SG, Paulo JA, Yim SH, Gygi SP, Chung JJ, Gladyshev VN.
The Journal of biological chemistry
doi: 10.1016/j.jbc.2022.102183
In vivo cyclic induction of the FOXM1 transcription factor delays natural and progeroid aging phenotypes and extends healthspan
Ribeiro R, Macedo JC, Costa M, Ustiyan V, Shindyapina AV, Tyshkovskiy A, Gomes RN, Castro JP, Kalin TV, Vasques-Nóvoa F, Nascimento DS, Dmitriev SE, Gladyshev VN, Kalinichenko VV, Logarinho E.
Nature aging
doi: 10.1038/s43587-022-00209-9
Selenophosphate synthetase 1 deficiency exacerbates osteoarthritis by dysregulating redox homeostasis
Kang D, Lee J, Jung J, Carlson BA, Chang MJ, Chang CB, Kang SB, Lee BC, Gladyshev VN, Hatfield DL, Lee BJ, Kim JH.
Nature communications
doi: 10.1038/s41467-022-28385-7
A chromosome-level genome of Antechinus flavipes provides a reference for an Australian marsupial genus with male death after mating
Tian R, Han K, Geng Y, Yang C, Shi C, Thomas PB, Pearce C, Moffatt K, Ma S, Xu S, Yang G, Zhou X, Gladyshev VN, Liu X, Fisher DO, Chopin LK, Leiner NO, Baker AM, Fan G, Seim I.
Molecular ecology resources
doi: 10.1111/1755-0998.13501
Biosensor-Linked Immunosorbent Assay for the Quantification of Methionine Oxidation in Target Proteins
Lee HM, Choi DW, Kim S, Lee A, Kim M, Roh YJ, Jo YH, Cho HY, Lee HJ, Lee SR, Tarrago L, Gladyshev VN, Kim JH, Lee BC.
ACS sensors
doi: 10.1021/acssensors.1c01819
SEPHS1: Its evolution, function and roles in development and diseases
Bang J, Kang D, Jung J, Yoo TJ, Shim MS, Gladyshev VN, Tsuji PA, Hatfield DL, Kim JH, Lee BJ.
Archives of biochemistry and biophysics
doi: 10.1016/j.abb.2022.109426
Epigenetic clocks, aging, and cancer
Johnstone SE, Gladyshev VN, Aryee MJ, Bernstein BE.
Science (New York, N.Y.)
doi: 10.1126/science.abn4009
Characterization of naked mole-rat hematopoiesis reveals unique stem and progenitor cell patterns and neotenic traits
Emmrich S, Trapp A, Tolibzoda Zakusilo F, Straight ME, Ying AK, Tyshkovskiy A, Mariotti M, Gray S, Zhang Z, Drage MG, Takasugi M, Klusmann JH, Gladyshev VN, Seluanov A, Gorbunova V.
The EMBO journal
doi: 10.15252/embj.2021109694
Redox regulation by TXNRD3 during epididymal maturation underlies capacitation-associated mitochondrial activity and sperm motility in mice
Wang H, Dou Q, Jeong KJ, Choi J, Gladyshev VN, Chung JJ.
The Journal of biological chemistry
doi: 10.1016/j.jbc.2022.102077